These AIs Are About to Revolutionize Biology

Even though proteins are fundamental to life, it’s hard to predict what they look like. But two independent groups announced that they’d cracked it, and it’s all thanks to some seriously clever artificial intelligence.Hosted by: Hank GreenSciShow is on TikTok! Check us out at https://www.tiktok.com/@scishow ----------Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow----------Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:Chris Peters, Matt Curls, Kevin Bealer, Jeffrey Mckishen, Jacob, Christopher R Boucher, Nazara, charles george, Christoph Schwanke, Ash, Silas Emrys, Eric Jensen, Adam, Brainard, Piya Shedden, Alex Hackman, James Knight, GrowingViolet, Sam Lutfi, Alisa Sherbow, Jason A Saslow, Dr. Melvin Sanicas, Melida Williams----------Looking for SciShow elsewhere on the internet?SciShow Tangents Podcast: http://www.scishowtangents.orgFacebook: http://www.facebook.com/scishowTwitter: http://www.twitter.com/scishowInstagram: http://instagram.com/thescishow----------Sources:https://www.nature.com/articles/s41586-021-03819-2https://www.nature.com/articles/d41586-021-01968-yhttps://science.sciencemag.org/content/early/2021/07/14/science.abj8754https://www.sciencemag.org/news/2021/07/researchers-unveil-phenomenal-new-ai-predicting-protein-structureshttps://www.ipd.uw.edu/2021/07/rosettafold-accurate-protein-structure-prediction-accessible-to-all/https://www.thetimes.co.uk/article/demis-hassabis-interview-the-kid-from-the-comp-who-founded-deepmind-and-cracked-a-mighty-riddle-of-science-g3v3z9b80https://www.technologyreview.com/2020/11/12/1011944/artificial-intelligence-replication-crisis-science-big-tech-google-deepmind-facebook-openai/https://www.technologyreview.com/2020/11/30/1012712/deepmind-protein-folding-ai-solved-biology-science-drugs-disease/https://news.cancerresearchuk.org/2020/12/23/what-could-deepmind-solving-the-protein-folding-problem-mean-for-cancer-research/https://www.theguardian.com/technology/2020/nov/30/deepmind-ai-cracks-50-year-old-problem-of-biology-researchhttps://arstechnica.com/science/2021/07/google-details-its-protein-folding-software-academics-offer-an-alternative/https://www.vox.com/future-perfect/22045713/ai-artificial-intelligence-deepmind-protein-foldinghttps://deepmind.com/blog/article/alphafold-a-solution-to-a-50-year-old-grand-challenge-in-biologyhttps://www.pnas.org/content/117/3/1496https://emerj.com/ai-sector-overviews/deepmind-alphafold/https://www.chemistryworld.com/opinion/behind-the-screens-of-alphafold/4012867.articlehttps://www.dw.com/en/what-are-proteins-and-why-do-they-fold/a-55815679https://www.nature.com/articles/d41586-020-03348-4https://www.nature.com/articles/s41586-021-03828-1https://www.nature.com/articles/d41586-021-02025-4https://www.theguardian.com/technology/2021/jul/22/ai-firm-deepmind-puts-database-building-blocks-life-human-protein-structure-free-onlinehttps://www.nature.com/articles/d41586-021-02037-0http://www.imgt.org/IMGTeducation/Aide-memoire/_UK/aminoacids/abbreviation.htmlhttps://www.ncbi.nlm.nih.gov/books/NBK26830/https://predictioncenter.org/casp14/doc/CASP14_press_release.htmlhttps://www.youtube.com/watch?v=gg7WjuFs8F4https://deepmind.com/blog/article/AlphaStar-Grandmaster-level-in-StarCraft-II-using-multi-agent-reinforcement-learninghttps://deepmind.com/blog/article/alphazero-shedding-new-light-grand-games-chess-shogi-and-gohttps://www.nobelprize.org/prizes/chemistry/1972/summary/https://www.frontiersin.org/articles/10.3389/fmolb.2020.00009/fullhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402234/https://www.youtube.com/watch?v=gLsC4wlrR2Ahttps://www.nature.com/articles/d41586-021-02265-4Images:https://commons.wikimedia.org/wiki/File:Hexokinase_ball_and_stick_model,_with_substrates_to_scale_copy.pnghttps://commons.wikimedia.org/w/index.php?curid=35438148https://wellcomecollection.org/works/u35a5anghttps://commons.wikimedia.org/wiki/File:Parasagittal_MRI_of_human_head_in_patient_with_benign_familial_macrocephaly_prior_to_brain_injury_(ANIMATED).gifhttps://commons.wikimedia.org/wiki/File:Target3dsmRib_354predictedModels_CASP8.jpghttps://commons.wikimedia.org/wiki/File:1GZX_Haemoglobin.pnghttps://www.eurekalert.org/multimedia/662832https://commons.wikimedia.org/wiki/File:Foldit_screenshot_2.jpghttps://commons.wikimedia.org/wiki/File:Neural_network_example.svgACBP_MSM_from_Folding@home.tiff">https://commons.wikimedia.org/wiki/File:ACBP_MSM_from_Folding@home.tiffhttps://commons.wikimedia.org/wiki/File:Structural_coverage_of_the_human_cyclophilin_family.pnghttps://commons.wikimedia.org/wiki/File:Protein_Imager_molecular_rendering_example_3_CsgFG_complex.pnghttps://commons.wikimedia.org/wiki/File:153-PyruvateDehydrogenaseComplex_pyruvatedehydrogenase.tifhttps://commons.wikimedia.org/wiki/File:Chaperonin_1AON.pnghttps://commons.wikimedia.org/wiki/File:Protein_structure_examples.png